Top 20 Startups Leading Agricultural Biotechnology in 2025

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Top 20 Startups Leading Agricultural Biotechnology in 2025

How is Biotechnology used in Agriculture?

Biotechnology plays a crucial role in modern agriculture by enhancing crop production and improving crop traits. Through genetic engineering techniques, scientists can introduce desirable traits into plants, such as resistance to pests, diseases, or environmental stress. Biotechnology also enables the development of genetically modified (GM) crops with increased nutritional value or improved post-harvest characteristics. Furthermore, biotechnology aids in the production of biofuels and bio-based materials from agricultural feedstocks, contributing to sustainable farming practices. Overall, biotechnology in agriculture helps increase crop yield, enhance food quality, and promote environmental sustainability. Agri biotechnology companies and bio agriculture companies are central to driving these advancements.

What are the Benefits of Agricultural Biotechnology?

Agricultural technology offers numerous benefits that positively impact the farming industry and global food production. Firstly, it improves efficiency by automating tasks, optimizing resource utilization, and reducing labor requirements. Secondly, it enhances productivity through precision farming techniques, such as GPS-guided equipment and sensor technologies, enabling farmers to make data-driven decisions for optimal crop management. Thirdly, agricultural technology improves sustainability by promoting sustainable farming practices, conserving resources, and minimizing environmental impact. Lastly, it facilitates access to information and markets, empowering farmers with real-time data, weather forecasts, market prices, and innovative platforms for selling their produce, thereby improving their economic viability. Agriculture startups play a significant role in developing these innovative technologies.

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The Agricultural Biotechnology Market

Agricultural biotechnology involves using different technologies applied to address and solve problems in all agricultural production and processing areas. These technologies include genetics, artificial intelligence (AI), microbiome research, and many more. The agricultural biotech industry has grown significantly and is projected to surpass $15 billion by 2025, driven by advancements in gene editing tools like CRISPR, microbiome innovations, and the rising demand for sustainable farming solutions. The increasing adoption of climate-resilient crops and biological alternatives to synthetic agrochemicals further drives this growth. Verified sources, such as industry reports, emphasize the pivotal role of agricultural biotech companies and plant biotech companies in achieving this progress.

Agriculture Biotech Companies that are Currently Changing the World

Here are the top 20 agricultural biotech startups to watch out for in 2025:

Agricycle

Located in Wisconsin, USA, Agricycle transforms food waste and agricultural byproducts into all-natural consumer-produced goods (CPG) brands sold in the US. It manufactures and sells technologies to rural farmers and teaches them how to preserve fruit with zero waste. It then buys the products created using its technology and sells them. Agricycle has partnerships with farming communities across Africa and the Caribbean, helping reduce food waste globally and improving livelihoods. Leading agricultural companies like Agricycle emphasize sustainability.

Pivot Bio
Based in California, USA, Pivot Bio focuses on nitrogen-fixing microbial solutions, reducing the need for synthetic fertilizers while improving crop yields. Their technology aligns with the demand for eco-friendly farming practices. In 2024, Pivot Bio launched new microbial strains tailored for cereal crops like maize and wheat, ensuring adaptability for diverse agricultural systems. Top agriculture companies often integrate such innovative solutions.

Benson HillHeadquartered in Missouri, USA, Benson Hill leverages AI and CRISPR technology to optimize crop genetics for higher protein content and better environmental resilience. Recent collaborations with global food companies have enabled the development of high-protein soybeans tailored for plant-based meat products. This solidifies their position among the biggest companies in agriculture focused on technology.

FYTO

Located in Massachusetts, USA, FYTO develops plant-based feed technology for the sustainable production of agricultural products. They offer nutrient-dense crops, climate-friendly methodologies, and biofertilizers to promote long-term sustainability. FYTO’s advancements in aquatic plant farming methods have enabled efficient water usage in drought-prone regions, making them a leader among plant biotechnology companies.


5Metis

Located in North Carolina, USA, 5Metis combines boron-based small molecule discovery and synthetic biology to create innovative solutions for crop protection. Their recent innovations include herbicides designed to combat glyphosate-resistant weeds, ensuring sustainable farming practices. Agricultural companies like 5Metis focus on sustainable crop protection solutions.

Indigo

Located in Massachusetts, USA, Indigo provides plant microbiome agricultural services to help increase crop yield and profitability. Their vast genomic microbe database identifies beneficial microbes for different crops and regions. Indigo’s recent launch of carbon sequestration programs enables farmers to adopt sustainable practices while earning carbon credits. Indigo Ag remains a key player among bio agriculture companies.

Biome Makers
Operating out of California, USA, Biome Makers focuses on microbiome research to develop soil health diagnostics and predictive analytics. Their “BeCrop” technology uses advanced microbial analysis to provide actionable soil health insights. Collaborations with academic institutions have validated their methods, positioning them among leading plant biology companies.

Lab Management Software for Agriculture and Life Sciences Startups: Scispot

Scispot is an advanced lab management and data automation platform designed for agriculture biotech companies and agricultural startups looking to streamline their R&D and operational workflows.

Unlike traditional electronic lab notebooks (ELNs) and laboratory information management systems (LIMS), Scispot provides an integrated alternative-LIMS and alternative-ELN solution that centralizes experimental data, automates research workflows, and enhances collaboration across teams. Its flexible architecture allows users to configure workflows specific to agricultural research, sample tracking, and inventory management.

With built-in automation and AI-driven analytics, Scispot enables data standardization, compliance tracking, and seamless integrations with instruments and third-party applications. Agricultural biotech companies leverage Scispot to manage everything from genomic data and field trials to microbiome research and biomanufacturing workflows.

By eliminating redundancies in traditional lab software, Scispot empowers agriculture biotech companies to scale faster, ensure regulatory compliance, and optimize lab productivity. Request a demo to see how Scispot can support your research and innovation.


Inari AgricultureBased in Massachusetts, USA, Inari customizes seed genetics using multiplex gene editing to improve crop performance. Recent partnerships with seed distributors have accelerated the adoption of their SEEDesign platform, placing them among the top plant biotech companies.

Reazent

Located in Nova Scotia, Canada, Reazent develops natural and safe agrochemicals for agriculture. Their latest products include a biostimulant line that improves root development in cereal crops. Reazent’s focus on plant immunity has earned them recognition as one of the innovative agriculture biotech companies.

Bioheuris

Located in Rosario, Argentina, Bioheuris uses synthetic biology and gene editing to develop herbicide-resistant crops that require fewer chemical inputs. Their collaboration with seed manufacturers has expanded their market presence in South America. They are among the largest agricultural companies advancing gene editing.


Bioprime Agrisolutions

Located in Maharashtra, India, Bioprime uses physiology-modulating biomolecules to build climate resilience in crops. Field studies have demonstrated improved yield in rice and sugarcane under extreme weather conditions. Bioprime is an innovative name among agricultural startups addressing climate challenges.

Toopi Organics

Located in Ecopôle, France, Toopi Organics processes human urine into natural fertilizers enriched with microorganisms. Verified results show a 15% yield improvement in pilot programs with European farms. Toopi Organics is a standout agricultural startup redefining waste recycling.

GreenPod Labs

Located in Tamil Nadu, India, GreenPods Labs provides post-harvest solutions that extend the shelf life of fruits and vegetables using nanotechnology. Their products have successfully reduced post-harvest losses in mango exports by 20%, highlighting their relevance among agricultural biotech companies.

Farmers Business Network (FBN)
Headquartered in California, USA, FBN’s platform integrates data-driven insights with financial services, enabling farmers to improve decision-making. Recent financing programs tailored to smallholders have strengthened FBN’s position among top agriculture companies supporting data-centric farming.

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Nutrilees

Located in Kiryat Shmona, Israel, Nutrilees transforms winemaking byproducts into nutrient-rich superfoods. Their expanded partnerships with European food brands showcase scalability, earning them recognition among the biggest companies in agriculture innovating food systems.

CEA Fresh Farms

Located in Georgia, USA, CEA Fresh Farms specializes in indoor hydroponic farming. Their energy-efficient farms have cut water usage by 90% compared to traditional methods. They are among the leading agricultural companies in sustainable indoor farming.

Lavie Bio

Located in Rehovot, Israel, Lavie Bio develops microbiome-based biopesticides. Recent approvals for their wheat biostimulant in the EU validate their progress, solidifying their role among bio agriculture companies.

Tropic BiosciencesLocated in Norwich, UK, Tropic Biosciences is pioneering disease-resistant banana varieties. Collaborations with African agricultural ministries have enabled large-scale trials, positioning them as innovators among agricultural companies.

MicroendoLocated in Jalisco, Mexico, Microendo customizes bio-fertilizers by leveraging plant microbiota. Their recent trials in coffee plantations improved yield by 18%. This advancement highlights their impact among plant biology companies.

RootWave

Located in England, UK, RootWave’s electric weed control technology has successfully replaced herbicides in commercial trials with wheat farms. Their work places them among agriculture biotech companies supporting sustainable practices.

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