Mass spectrometry (MS) is one of the most versatile and precise analytical techniques available today. It provides accurate identification, quantification, and structural analysis of molecules within a sample. This technology plays a critical role in industries such as pharmaceuticals, biotechnology, environmental science, and forensics.
By enabling researchers to detect impurities, understand molecular structures, and measure biomolecules with extreme precision, mass spectrometry solutions have become indispensable tools for driving scientific and industrial innovation. In this mass spectrometry blog, we spotlight the top 10 mass spectrometry companies in North America that are making waves in 2025.
Location: Ann Arbor, Michigan, USA
MS Bioworks LLC specializes in advanced proteomics, focusing on quantitative proteomics, phosphoproteomics, and tailored workflows for unique client requirements. Their expertise lies in label-free quantitation, SILAC, and TMT-based approaches, offering flexibility for diverse research needs.
They serve as one of the leading proteomics CROs, supporting clients in academia, biotech, and pharma. They are particularly well-known for their role in early-stage biomarker discovery, where their ms bioworks proteomics analysis excels in identifying low-abundance proteins. MS Bioworks also offers customizable data pipelines, making them a trusted partner for complex projects requiring intricate bioinformatics.
Key Strengths:
- Expertise in post-translational modifications (PTMs).
- Advanced instrumentation, including Thermo Fisher Orbitrap mass spectrometers.
- Transparent reporting and strong customer support.
Location: Sherbrooke, Quebec, Canada
Allumiqs (formerly Phenoswitch Bioscience) is a top mass spectrometry company that has carved a niche in proteomics and metabolomics. They are recognized for their ability to integrate mass spectrometry services with bioinformatics to generate actionable insights. In 2025, they have expanded their services to include lipidomics and glycomics, enhancing their multi-omics capabilities.
The company's focus on innovation is evident in their development of personalized workflows, particularly for pharmaceutical companies tackling complex challenges in oncology and precision medicine. Allumiqs is also exploring AI-driven data analysis to automate parts of their metabolomic profiling.
Key Strengths:
- Deep expertise in metabolite identification and quantification.
- Collaborations with top universities for cutting-edge research.
- Proprietary tools for efficient metabolomics data interpretation.
Location: Wilmington, North Carolina, USA
As part of Thermo Fisher Scientific, PPD Laboratories offers comprehensive mass spectrometry services for small and large molecules. They specialize in developing validated bioanalytical methods, crucial for regulatory submissions. Their offerings in mass spec services include metabolite identification, biomarker quantification, and protein characterization.
PPD has also expanded its use of high-resolution mass spectrometry in 2025, enabling them to deliver ultra-sensitive analyses for biologics and biosimilars. Their robust global infrastructure ensures consistent data quality across multi-site clinical trials, making them a leader among mass spec companies.
Key Strengths:
- Strong compliance record with FDA, EMA, and other regulatory bodies.
- Focus on quantitative bioanalysis for pharmacokinetics and pharmacodynamics.
- Enhanced capabilities in handling complex biologics and peptides.
Location: Shirley, New York, USA
Creative Proteomics stands out as a versatile mass spectrometry company offering a broad spectrum of services, including proteomics, metabolomics, lipidomics, and glycomics. They cater to clients in diverse industries, including agriculture, food safety, and personalized medicine.
In 2025, Creative Proteomics has expanded its capabilities in targeted lipidomics, addressing the growing demand for understanding lipid-related disorders. Their focus on customized solutions ensures they meet the unique needs of every client, whether it’s academic research or pharmaceutical development.
Key Strengths:
- Expertise in multi-omics research and integrated workflows.
- Advanced instrumentation like Q-TOF and Orbitrap mass spectrometers.
- Strong bioinformatics support for data analysis and visualization.
Location: Princeton, New Jersey, USA
Novatia has built a strong reputation as a specialized mass spectrometry company, tackling challenges in small molecule analysis, peptide synthesis, and oligonucleotide characterization. Their team excels in method development, particularly for complex analytical problems in synthetic chemistry and drug discovery.
In 2025, Novatia has introduced enhanced high-throughput capabilities for pharmaceutical clients, enabling faster drug formulation studies. Their expertise in mass spec service workflows ensures high accuracy, even in challenging matrices.
Key Strengths:
- Focused expertise in niche areas like oligonucleotide therapeutics.
- Reliable support for analytical method validation.
- Partnerships with pharmaceutical companies for quality control testing.
Location: Wilmington, Massachusetts, USA
Charles River Laboratories has expanded its portfolio of mass spectrometry solutions to include isotopic labeling for metabolic pathway elucidation and stable isotope tracing. Their services cater to pharmaceutical companies looking to gain deeper insights into drug metabolism and disease mechanisms.
In addition to preclinical support, Charles River is now focusing on scalable workflows for early-stage clinical trials, making them a key player among mass spec companies.
Key Strengths:
- Expertise in biomarker discovery and metabolic pathway analysis.
- Strong global presence for scalable solutions.
- Advanced tools for combining proteomics and metabolomics data.
Location: Durham, North Carolina, USA
BioAgilytix has positioned itself as a trusted proteomics CRO, offering advanced mass spectrometry lab services for large molecule bioanalysis. Their expertise spans ultra-sensitive biomarker quantification, pharmacokinetics, and immunogenicity assessments.
Their focus on regulatory compliance ensures that clients receive validated data suitable for FDA and EMA submissions, making them one of the most reliable mass spectrometry companies in the biotech industry.
Key Strengths:
- Innovative assays for antibody-drug conjugates and cell therapy products.
- Stringent quality control processes.
- Industry-leading turnaround times for project delivery.
Location: San Diego, California, USA
Omics Solutions integrates advanced bioinformatics with mass spectrometry services, enabling clients to extract meaningful insights from complex datasets. Their AI-powered platforms are redefining how researchers approach proteomics and metabolomics.
Their tailored workflows cater to a wide range of industries, from environmental science to agricultural biotechnology, showcasing their versatility as a mass spectrometry company.
Key Strengths:
- AI-driven solutions for data interpretation.
- Integration with mass spectrometer manufacturers for seamless workflows.
- Applications in bioremediation and precision agriculture.
Location: Burlington, North Carolina, USA
Labcorp Drug Development excels in providing mass spectrometry services for bioanalytical studies. In 2025, they have scaled up their targeted biomarker analysis services, with a particular focus on immuno-oncology and rare disease research.
Their ability to design custom workflows makes them a leader among mass spectrometry companies for multi-site clinical trials.
Key Strengths:
- Focus on rare disease biomarkers and immuno-oncology.
- Scalable solutions for large-scale studies.
- Comprehensive support for data standardization and traceability.
Location: Laval, Quebec, Canada
Altasciences is a full-service mass spectrometry lab that leverages hybrid techniques to accelerate drug development. Their focus on biologics and biosimilars ensures cost-effective solutions without compromising quality.
Their integration with mass spec manufacturers has streamlined workflows for clients seeking regulatory compliance.
Key Strengths:
- Hybrid mass spectrometry for structural elucidation and quantification.
- Cost-efficient solutions tailored for small and mid-sized biotech firms.
- Expertise in biologics and biosimilar analytics.
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