One Unified Platform for High-Throughput Proteomics Workflows

Centralize, automate, and streamline your proteomics workflows with advanced integration and real-time data insights. Scispot is the alternative to legacy proteomics LIMS, ELN, and SDMS systems—designed for the unique needs of proteomics researchers in modern labs.
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Standardized Proteomics Data Model & Integration

Precisely capture protein sequences, post-translational modifications (PTMs), and experimental metadata, facilitating streamlined data management and FAIR compliance in your proteomics lab.

Automated Workflows and Collaboration

Accelerate high-throughput proteomics using advanced AI-driven automation for multi-well plate workflows

Advanced Protein Analytics & Visualization

Rapidly visualize proteomics data with specialized charts such as volcano plots, PCA plots, and protein interaction networks.
Outcomes

Complete Proteomics Visibility with AI-Driven Insights

Real-time tracking of proteomics workflows—from peptide digestion through LC-MS/MS analysis—to ensure experimental clarity and reproducibility.
Centralize proteomics-specific data (mzML, mzIdentML, mzTab), protein sequences, PTMs, and metadata for FAIR-compliant management.
Instantly create visualizations (volcano plots, protein interaction networks) directly from raw mass spectrometry data, reducing analysis time by 70%.
Connect raw spectral data with protein annotations using Scispot’s proteomics knowledge graph, uncovering deeper biological insights.
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Outcomes

Streamlined Workflows with Automated Processing

Automatically capture data from proteomics instruments (Orbitrap, TripleTOF), chromatography systems, and liquid handlers, eliminating manual entry.
Standardize proteomics protocols (digestion, fractionation, MS/MS) with version-controlled workflows and intuitive templates, ensuring reproducibility.
Automate routine proteomics tasks—digestion tracking, fractionation monitoring, spectral analysis—to increase productivity by up to 3x.
Reduce experiment setup time by 40% and accelerate data processing by 80% through seamless LabOS-to-instrument integration.
Outcomes

Real-Time Multi-User Collaboration

Enable concurrent workflow access with defined permissions for wet lab scientists, mass spec specialists, bioinformaticians, and QA/QC teams.
Rapidly share proteomics results and pathway analyses through collaborative dashboards with instant updates.
Maintain a comprehensive digital audit trail of protocol modifications, ensuring consistency across collaborative or multi-site projects.
Unify experimental and computational proteomics teams in shared workspaces, bridging gaps between MS data and bioinformatics analysis.
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Outcomes

Comprehensive Regulatory Compliance

Automate compliance management (FDA, ISO, GxP, CFR Part 11) for proteomics workflows, simplifying clinical biomarker validation and regulated studies.
Generate audit-ready reports with electronic signatures for regulatory submissions, streamlining documentation while preserving data integrity.
Protect sensitive proteomics data with secure AWS cloud infrastructure, encryption, and detailed electronic audit trails.
Monitor assay quality, instrument performance, and compliance metrics proactively, addressing potential issues before they affect timelines or quality.

Why Choose Scispot

API-First and Built-In Integrations

Connect with major mass spectrometry instruments and proteomics software through built-in integrations or APIs.

Scalable Infrastructure

Scales from small projects to large studies with flexible infrastructure supporting academic to pharmaceutical research growth.

AI-Driven Insights

Leverage AI analytics to optimize experiments, identify patterns, predict issues, and extract insights from complex proteomics data.

Built-In Compliance

Maintain regulatory compliance with automated audit trails, quality checks, and secure data handling for research and clinical applications.

Use Cases & Real-World Applications

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Biomarker Discovery and Validation

Scispot accelerates biomarker discovery workflows by centralizing and automating proteomics data from peptide digestion through LC-MS/MS quantification. Labs can efficiently manage large cohorts of clinical samples, automate statistical validation of candidate protein biomarkers, and ensure reproducibility across large-scale proteomics initiatives, such as plasma-based biomarker validation using Orbitrap or Q-TOF systems.
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Clinical Proteomics Research

Scispot simplifies clinical proteomics by automating end-to-end data management—from patient sample accessioning and proteomic sample prep (e.g., digestion, depletion, fractionation) to mass spectrometry analysis and regulatory reporting. Real-time data integration from clinical mass spectrometry instruments, automated QC checks, and integrated compliance management (ISO, FDA, CFR Part 11) ensure regulatory readiness and complete sample-to-result traceability, vital for protein-based diagnostic assays.
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Structural Proteomics Analysis

Scispot streamlines structural proteomics research by organizing complex data from methods like hydrogen-deuterium exchange (HDX-MS), cross-linking mass spectrometry (XL-MS), and native MS. The platform automates sample preparation tracking, precisely captures instrument parameters (e.g., labeling conditions, cross-linkers), and integrates computational analysis outputs, enabling rapid interpretation of structural data to elucidate protein conformations, interactions, and dynamics relevant to drug discovery.
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Post-Translational Modification Studies

Scispot automates complex PTM proteomics workflows, enabling efficient tracking of enrichment protocols, specialized MS techniques (e.g., phosphopeptide enrichment, glycopeptide analysis), and PTM localization data. Customizable data fields capture site-specific PTM information, while integrated visualization and analytics tools rapidly identify modification patterns across experimental conditions. Direct integration with bioinformatics pipelines allows researchers to correlate PTM data with functional outcomes, accelerating insights into signaling mechanisms and disease pathways.

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Resources

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FAQs

How does Scispot integrate with our existing mass spectrometry instruments and proteomics software?

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Scispot provides seamless, real-time integration with mass spectrometry instruments such as Thermo Fisher Orbitrap, SCIEX TripleTOF, Bruker timsTOF, and Waters SYNAPT through built-in connectors and an API-first design. Raw data flows directly from instruments to Scispot without manual intervention, enabling instant data availability. Scispot also smoothly integrates with leading proteomics analysis software, including MaxQuant, Proteome Discoverer, and Skyline, delivering a streamlined, end-to-end proteomics solution. Additionally, Scispot's flexible API enables quick integration of your custom analytical pipelines and specialized software.

How can Scispot help us manage the massive amounts of data generated in our proteomics experiments?

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Scispot is purpose-built for the large-scale data management needs of proteomics labs, efficiently handling terabytes of raw mass spectrometry data. The platform organizes and links spectral files, peptide/protein identifications, experimental metadata, and sample information in a unified data lake. With built-in metadata tracking and intuitive querying, Scispot ensures complete data provenance and reproducibility. Its scalable infrastructure adapts effortlessly as your proteomics data volumes grow, providing rapid data access, interactive visualizations, and secure long-term archiving—all optimized specifically for proteomics workflows.

Do we need a dedicated IT team to configure and manage Scispot for our proteomics lab?

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No dedicated IT team is required. Scispot's intuitive, no-code platform empowers proteomics researchers to configure complex workflows, data structures, and instrument integrations quickly through a simple drag-and-drop interface. The platform is easy to set up, allowing lab members to customize proteomics assays, automate mass spec data capture, and manage experimental protocols independently. Scispot's dedicated white-glove support ensures rapid implementation (typically weeks, not months), ongoing optimization, and training—so your team can concentrate entirely on proteomics science, not software administration.

How does Scispot enhance collaboration between wet lab scientists and bioinformaticians in proteomics research?

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Scispot bridges the gap between experimental proteomics teams and computational analysts through a unified, collaborative workspace. Wet lab scientists can seamlessly document protocols, monitor sample processing steps, and track instrument parameters, while bioinformaticians have immediate access to raw spectral data, quantification results, and analysis outputs within the same platform. Real-time notifications and a dedicated proteomics knowledge graph allow teams to instantly share insights, visualize complex protein interaction networks, and collaborate effectively—accelerating discovery from raw mass spec data to meaningful biological insights.

Can Scispot handle specialized proteomics workflows like PTM analysis or targeted quantification?

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Yes, Scispot is specifically designed to support advanced proteomics applications. For post-translational modification (PTM) studies, Scispot efficiently tracks enrichment protocols, fragmentation methods, and precise site-localization data. In targeted proteomics (e.g., parallel reaction monitoring [PRM], selected reaction monitoring [SRM]), the platform manages transition lists, calibration standards, and quantitative results, linking them clearly to sample conditions. Scispot’s flexible data structures and no-code workflow engine rapidly adapt to emerging proteomics methods, including top-down proteomics or complex metaproteomics projects, ensuring your lab stays at the forefront of proteomics innovation.

How does Scispot streamline the management of protein stability conditions during sample processing?

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Scispot provides precise control for protein stability through automated alerts and real-time tracking. Users can set custom conditions like temperature thresholds, freeze-thaw cycles, and expiry timelines specific to protein samples. The system maintains parent-child aliquot relationships and tracks locations within freezers, ensuring that proteomics samples maintain optimal conditions from receipt to analysis.

How does Scispot enable multi-omics integration for comprehensive proteomics analysis?

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Scispot functions as a scientific data lake house, enabling seamless integration of proteomics data with genomics, metabolomics, and other omics datasets. Through structured JSON formats in a graph database, the system preserves complex relationships and experimental contexts. Researchers can push, pull, and interlink diverse data types for unified, deeper insights across multiple scientific domains.